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Joined: 23 Apr 2018 Posts: 1926
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Posted: 27-04-2018 04:36:41 Post subject: by Chris Mgidu |
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SAN FRANCISCO Vans Old Skool Canvas White Sale , July 23 (Xinhua) -- Researchers at the University of Washington (UW) have discovered a simple way, by adding polydopamine to diagnostic tests for medicine and common assays for laboratory research at a key step, to raise the accuracy of these tests.
Polydopamine, a material first isolated from shellfish, could help increase the sensitivity of the tests by as many as 100 to 1,000 times.
"Common bioassays are the real workhorses of laboratory experiments and medical tests Online Vans Leather Old Skool Reissue DX White ," said Xiaohu Gao, a UW professor of bioengineering. "By boosting the sensitivity of these tests, we can enable more accurate medical diagnoses earlier in a disease or condition, and enable more certainty and less waste in the research process."
More sensitive tests would allow scientists to identify pathogens, diseases and specific cellular proteins even when these "biomarkers" are present at levels far below the detection threshold of today's standard tests. Initial results show polydopamine boosted the accuracy and resolution of these tests for biomarkers of HIV, Zika virus and proteins on cancerous tumors.
Gao led the team that developed this modification for common medical and laboratory assays and recently published their approach Vans Perf Leather Old Skool Zip White Clearance , known as enzyme-accelerated signal enhancement, or EASE, in Nature Biomedical Engineering.
EASE centers on the addition of two biochemical components, dopamine and horseradish peroxidase, or HRP, at a key step. HRP is a common protein enzyme used to speed up the rate of reactions in biomedical research. Gao's team discovered that HRP can connect dopamine molecules together to form the polymer chain polydopamine. Polydopamine Online Vans Old Skool Leather Zip White , in turn, accumulates on the surfaces of reaction vessels. Once the polydopamine is present, researchers can continue the traditional steps of their protocols, but now with a substantially increased test sensitivity.
"Scientists have been trying to improve the accuracy of these common tests for decades, but solutions often involve entirely new protocols or costly pieces of equipment," explained Gao. "Understandably Vans Old Skool Pro Black Gum Shoes Sale , researchers can be reluctant to invest in unfamiliar protocols or expensive new equipment, but EASE is a simple addition to tried-and-true assays. It's like a software upgrade, instead of changing your operating system."
These assays include some of the most common medical and laboratory tests. Some of these assays have been used for decades to help hospitals and doctors detect signatures of a disease, ailment or other conditions by looking at a patient's blood, other body fluids or cells. Depending on the test, these telltale signs could be pieces of a bacteria or virus Wholesale Vans LXVI Old Skool Lite Black White , a chemical, antibodies made by white blood cells, a hormone or even pieces of deoxyribonucleic acid (DNA).
If these compounds are present at extremely low levels, diagnostic tests can miss them and return inaccurate medical information. By increasing sensitivity, EASE reduces uncertainty and increases the amount of information these tests can provide. For example, the team used EASE to detect the presence of Zika virus in the placental tissues of primates. EASE made the assay so sensitive that the team was able to see which types of cells within the placenta were infected with Zika.
Gao was quoted as saying in a news release from UW that he hopes this simple modification will mean that scientists and medical professionals can easily incorporate EASE into their common practices and procedures.
BEIJING Clearance Vans Leather Old Skool Reissue DX Black , March 2 (Xinhua) -- Jiangsu Suning got some paid off as record signing Alex Teixeira scored his first goal with the club to help them beat Jeonbuk Motors 3-2 in the Asian Champions League on Tuesday.
Jiangsu paid 50 million euros (about 54 million US dollars) for Brazilian star Teixeira from Shakhtar Donetsk on February days after their 28-million-euro (about 30 million US dollars) purchase of Ramires from Chelsea.
Teixeira scored Jiangsu's opener in the 16th minute with a low shot from outside the area. Former Everton and Manchester City striker Jo and Wu Xi restored the host's advantage in the 66th and 69th minutes respectively after Lee Dong-Gook's equalizer in the 61st minute.
Jeonbuk Motors made it 3-2 after an own goal by Jiangsu in the end of the second half.
Ramires was sent off for a push in injury time.
Jiangsu moved to the top of Group E with four points from two games. FC Tokyo is level on points with Jeonbuk after beating Binh Duong 3-1 at home.
Another Chinese club Shandong Luneng also claimed a victory as they beat Thai winners Buriram United 3-0 on Tuesday.
Shandong has so far won four games and scored 13 goals under the guidance of Menezes, the former boss of Brazil's national team.
The Chinese Super League has spent almost 300 million US dollars on players in the winter transfer window, which made the competition of the Asian Champions League this season more fierce.
Guangzhou Evergrande has won two of the last three Asian Champions League tournaments, while the other Chinese clubs have struggled.
Chinese soccer fans expect to see the recent investments can make a difference for clubs like Jiangsu, Shanghai and Shandong.
by Chris Mgidu
NAIROBI, Sept. 26 (Xinhua) -- Sudden-onset natural hazards adidas stan smith australia , primarily floods, caused more than 600,000 new displacements in 2016 in the Greater Horn of Africa, a new report by an international charity published on Tuesday shows.
The Norwegian Refugee Council (NRC)'s Internal Displacement Monitoring Centre (IDMC) highlights the need for more investment to track the number of the displaced to strengthen the resilience of displaced communities and their hosts.
"The need to address the risk and impacts of disaster displacement, which will be made worse by climate change, is a global and regional policy priority adidas superstar black australia ," said Justin Ginnetti, head . |
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